Application
This Anti-Integrin β1 Antibody, clone 21C8, azide free is validated for use in FC, IP, FUNC, IH for the detection of Integrin β1.
Research Sub CategoryIntegrins
Research CategoryCell Structure
Immunoprecipitation
Immunohistochemistry on frozen sections
Flow cytometry
Stimulates adhesion of cells to extracellular matrix proteins (Wilkins et al., 1996)
Does not bind reduced beta1 integrin on Western blot
Optimal working dilutions must be determined by end user.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
source is Jurkat T-leukemic cell line
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Purified immunoglobilin. Liquid in PBS, no preservatives.
Format: Purified
Specificity
Reacts with the human integrin beta1 subunit. Specificity verified by preclearing of beta1in immunoprecipitation, flow cytometry on transfectant cells displaying human beta1 integrin, and reactivity with purified beta1. Recognizes distinct elements within the same epitope cluster bound by MAB2251.(Wilkins et al., 1996)
Storage and Stability
Aliquot using sterile technique and maintain at 2-8°C.
This product has met the following criteria to qualify for the following awards: